What is 5htp good for
Apr 12, 2021

What is 5htp good for

5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation. Since 5-HTP increases the synthesis of serotonin, it is used for several diseases where serotonin is believed to play an important role including depression, insomnia, obesity, and many other conditions.

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What does 5htp good for

These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious, and should be evaluated by a qualified healthcare provider.

Cerebellar ataxia

5-HTP has been observed to have benefits in some people who have difficulty standing or walking because of cerebellar ataxia. However, current evidence is mixed.


Studies suggest that 5-HTP may reduce eating behaviors, lessen caloric intake, and promote weight loss in obese individuals.

Alcoholism (withdrawal symptoms)

Early research suggests that 5-HTP may lessen alcohol withdrawal symptoms. Further research is needed before a conclusion can be made.


Although 5-HTP has been proposed as a possible treatment for anxiety disorders, sufficient human evidence to make a firm conclusion is lacking.


The results of numerous studies in humans suggest that 5-HTP may aid in the treatment of depression. However, it is not known whether 5-HTP is as effective as commonly prescribed antidepressant drugs.

Down's syndrome

Preliminary research on 5-HTP in children with Down's syndrome has yielded insignificant results. Further research is necessary.


There is a small amount of research evaluating the use of 5-HTP for fibromyalgia. Early evidence suggests that 5-HTP may reduce the number of tender points, anxiety, and the intensity of pain, and may improve sleep, fatigue, and morning stiffness. Further research is needed before a conclusion can be made.


Several studies, in both children and adults, suggest that 5-HTP may be effective in reducing the severity and frequency of headaches, including tension headaches and migraines. Further research is needed.


In early research, 5-HTP lacked an effect on mood in healthy, young subjects. However, in this population, 5-HTP may impair decision-making. Further well-designed research is needed.

Neurologic disorders

5-HTP has been studied in panic disorder and various neurologic disorders. Additional clinical research is needed before conclusions can be made.

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Parkinson's disease

Parkinson's disease is a neurological disorder that usually develops around the age of 50. The disorder occurs when the brain cells that make dopamine slowly degenerate. Symptoms include tremors (shaking) and difficulties with movement and coordination. 5-HTP has been studied, usually in combination with drugs, for Parkinson's disease.

Psychiatric disorders

It has been suggested that 5-HTP may reduce psychotic symptoms and mania in panic disorder, but studies in people with schizophrenia have shown mixed results.

Sleep disorders

Insufficient evidence is currently available regarding the use of 5-HTP for sleep disorders. Additional studies are needed before a conclusion can be drawn.

Hot flashes

Limited research suggests that 5-HTP may be ineffective for reducing hot flash frequency in postmenopausal women. Further research is required before firm conclusions can be drawn.

Seizures/epilepsy (myoclonic disorders)

Although 5-HTP has been studied as a treatment for various myoclonic syndromes and epilepsy, available research does not support the use of 5-HTP for these conditions.

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Is 5 htp good for anxiety

5-hydroxytryptophan (5-HTP) can be converted to serotonin in the body. It is often used for depression. It has less evidence for insomnia and anxiety.

Is 5 htp good for sleep

Sleep and sleep-wake cycles

Because of its role in creating serotonin, 5-HTP is indirectly involved in producing melatonin, a hormone that is critical for sleep. Melatonin helps the body’s bio clock stay in sync, and regulates daily sleep-wake cycles. A strong bio clock and regular sleep-wake routines are the cornerstones of healthy, restful, rejuvenating sleep. Research suggests that 5-HTP may help shorten the time it takes to fall asleep and increase sleep amounts.

Is 5htp good for pms

For PMS, 5-HTP works to increase serotonin production which can alleviate symptoms of premenstrual depression, anxiety and sleeplessness. 5-Hydroxytryptophan (5-HTP) is produced in the body from the essential amino acid L-tryptophan. An amino acid is “essential” when it cannot be made in the body and must come from food or supplementation. Taking 5-HTP as a supplement gives the central nervous system a crucial building block with which to produce more serotonin.

Is 5 htp good for ocd

Clinicians around the globe, for more than twenty years, have had success with amino precursors including 5-HTP for the treatment of OCD. I recommend starting all patients with 50 mg of 5-HTP and titrate slowly every 2 weeks up to a maximum of 200 mg per day. Side effects of 5-HTP include nausea, irritability, and possible anxiety.

Is 5 htp good for adhd

5-HTP (5-Hydroxytryptophan) is a chemical by-product of the protein building block L-tryptophan. It is also produced commercially from the seeds of an African plant known as Griffonia simplicifolia 5-HTP is used for sleep disorders such as insomnia, depression, anxiety, migraine and tension-type headaches, fibromyalgia, obesity, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), attention deficit-hyperactivity disorder (ADHD), seizure disorder, and Parkinson's disease.

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Is 5 htp good for headaches

5-HTP is said to help with migraines, which are throbbing headaches that are often accompanied by nausea or disturbed vision. While their exact cause is debated, some researchers believe they are triggered by low serotonin levels.

Is 5 htp good for menopause

Scientific evidence shows 5-HTP may also be able to reduce the frequency of migraine headache attacks and reduce pain from chronic headaches. Many women experience headaches and migraines during menopause.

Is 5 htp good for pain

5-HTP (5-Hydroxytryptophan) is a building block of serotonin. Serotonin is a powerful brain chemical, and serotonin levels play a significant role in fibromyalgia pain. Serotonin levels are also associated with depression and sleep.

For those with fibromyalgia, 5-HTP may help to increase deep sleep and reduce pain. In one study published in the Alternative Medicine Review, researchers reported that supplementation with 5-HTP may improve symptoms of depression, anxiety, insomnia, and fibromyalgia pains. However, there are some contradictory studies that show no benefit with 5-HTP.

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