Yes. Allulose has received Generally Recognized As Safe (GRAS) status from the U.S. Food and Drug Administration (FDA). Based on FDA guidance, people of all ages can enjoy allulose in foods and beverages.
In dogs, oral administration of a high dose of D-allulose (1 and 4 g/kg) has been shown to cause only self-limiting gastrointestinal symptoms and a transient rise in plasma alkaline phosphatase activity. These results suggested that a single-dose administration of D-allulose does not cause acute toxicity in dogs.
Allulose is suitable for individuals with diabetes. "In acute studies on subjects with type 2 diabetes or impaired handling of blood glucose, ingestion of allulose not only does not affect blood glucose but also improves metabolic handling and lower glycemic response of high-glucose carbohydrates," Sievenpiper says. "It activates the enzyme glucokinase in hepatocytes, promoting glycolysis by increasing conversion of glucose to glycogen."
Allulose is a real 100% natural sugar without calories. In pet food, Allulose is used as a calorie-free, tooth-friendly sweetener. Allulose can also be used for coloring reasons (Maillard reaction). Pets love the Allulose taste; which leads to an improved feed acceptance. Studies confirms that Allulose -as a calorie-free monosaccharide- lowers blood lipid levels; It is therefore suitable for the diet of obese or diabetic animals.
While some people think that swapping sugar for artificial sweeteners is an easy way to reduce their kids’ sugar consumption, a lot of questions about them still remain. Are artificial sweeteners safe for kids to consume? And do they actually help with weight loss? Unfortunately, the answers aren’t exactly straightforward.
According to the U.S. Food and Drug Administration, allulose is generally recognized as safe, meaning that it can be used as a food additive and sweetener in products sold in the United States.
However, it is still not permitted in many other areas, including Europe.
Studies in humans and animals show that it can be safely consumed in moderation with little to no side effects, even after long-term use. Some of the most commonly reported allulose side effects include digestive issues, such as bloating, gas and diarrhea.
Rats supplemented with five-percent D-psicose (allulose) showed the same blood sugar regulation benefits as humans, as well as lower body weights. However, they had significantly heavier livers than the fructose-supplemented controls (Matsuo & Izumori, 2006; Biosci Biotechnol Biochem.; 70(9):2081-5.)
These are not unique findings: a one-time dose of radioactive allulose was found to accumulate in the livers, kidneys, and bladders of both rats and mice (Tsukamoto et al. 2014; Drug Des Devel Ther.; 8:1955-64. doi: 10.2147/DDDT.S60247), and there is also evidence of fatty degeneration and fibrosis in the liver with allulose consumption.
To make allulose, Tate & Lyle starts with corn, breaks it down into starch and fructose and then converts the fructose to allulose via an enzymatic conversion process using enzymes from a genetically engineered microbe. The enzymes – which serve as processing aids - are not in the final product, however.
Unlike stevia, monk fruit and erythritol, allulose is an actual sugar that is chemically similar to table sugar. It has a similar taste and texture, as well as the same browning properties as sugar. It's about 70% as sweet as sugar, meaning that a little more would be needed to substitute for sugar in a recipe.
Is Allulose an Artificial Sweetener? No. allulose is classified as a “rare sugar,” because it's naturally found in small amounts in a few foods—including figs, raisins, molasses, and maple syrup. Like glucose and fructose—the two components that make up sucrose, or table sugar,—it's a "monosaccharide," or simple sugar.