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Why is inulin administration an effective way of measuring renal clearance rates?
Mar 30, 2021

Why is inulin administration an effective way of measuring renal clearance rates?

Because it is not secreted and reabsorbed.

Inulin clearance is done by which the filtering capacity of the glomeruli is determined by measuring the rate at which inulin is cleared from the plasma. It is considered as the most accurate substance to use because it is inert polyssacharide that passes readily in the glomeruli without being reabsorbed in the tubules. Inulin is seldom used in clinical testing but used in research. Creatinine clearance is the more commonly used test to assess function of kidney clinically.

inulin

Why is inulin administration an effective way of measuring renal clearance rates?

Inulin is filtered and completely reabsorbed in the distal tubule.

It is not filtered by the glomerulus.

Inulin is neither secreted nor reabsorbed.

Inulin is freely filtered and secreted.

When the macula densa detects an increase in NaCl concentration in the renal filtrate, what happens to the glomerular filtration rate (GFR)?

GFR decreases.

GFR increases.

GFR stays the same

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