Animal studies have found evidence that chlorogenic acids from green coffee bean extract can reduce blood pressure. 1 Based on this, researchers have conducted human trials.
In a double-blind, placebo-controlled study of 117 males with mild hypertension , green coffee bean extract was given for one month at 46 mg, 93 mg, or 185 mg daily. 2 After 28 days, the results showed a significant improvement in blood pressure as compared to placebo in the 93 mg and 185 mg groups. The results seen were dose-related, meaning that the greater the dose, the greater the improvement. The finding of dose-relatedness tends to increase the likelihood that a studied treatment is actually effective. Antihypertensive benefits were also seen in a much smaller study using purified chlorogenic acids.
green coffee bean extract has also shown a bit of promise for aiding weight loss4 , perhaps in part due to its chlorogenic acid content. 5 The caffeine in GCBE might also provide a slight weight loss benefit.
green coffee bean extract products are sometimes said to help prevent diabetes; however, this claim derives only from weak evidence involving consumption of ordinary coffee, 6 and cannot be relied upon at all.
Roasted (as opposed to green) coffee beans contain the substances kahweol and cafestol, which appear to increase levels of LDL ("bad" cholesterol). 7 The fact that GCBE does not contain these substances is used as an argument in its favor. However, these substances remain in the coffee grounds and so they are also not present in standard beverage coffee, so this is probably not a significant point. (Unfiltered or boiled coffee, with the grounds left in, however, may present a risk.)
In the large human trial of green coffee bean extract for hypertension noted above, the extract was most effective when taken at a dose of 185 mg daily.
Since green coffee bean extract typically contains about 30% chlorogenic acids, this works out to a dose of about 60 mg of chlorogenic acids daily. Another study used 140 mg of purified chlorogenic acids daily.
GCBE is thought to be a safe substance. In human trials, no significant adverse effects have been seen.
In theory, the caffeine content of GCBE could potentially cause problems for some people. However, since green coffee bean extract contains only about 10% caffeine by weight, a high daily dose contains no more than about 20% of the caffeine content of a strong cup of coffee.
Maximum safe doses in pregnant or nursing women, young children, or people with liver or kidney disease have not been established.
If you are pregnant, may become pregnant or are nursing, please consult your healthcare professional before using this product. Each tablet has less than 25mg of naturally occurring caffeine, which is equivalent to approximately 1/4 cup of coffee.
According to Caffeine Informer, one popular brand of green coffee extract contains 50 mg of caffeine per capsule and the recommended dosage is two capsules before every meal for an average dose, three for a moderate dose and four capsules for an accelerated dose. Other brands contains between 20 and 40 mg of caffeine.
Green coffee contains chlorogenic acid, a powerful antioxidant that tends to break down when coffee beans are roasted. Some research suggests that the retention of chlorogenic acid in green coffee is largely responsible for the health benefits.
Although research is limited, there is evidence that green coffee can stimulate metabolism (the conversion of calories and oxygen into energy). Metabolism doesn't only imply digestion; it dictates how well all cells in the body function, including those of the heart, lung, kidney, liver, and brain.
Here is just some of what the current research says about the benefits of green coffee:
Green coffee may be moderately beneficial to those trying to lose weight, according to a review of studies published in Gastroenterology Research and Practice.2 Of the three clinical trials included in the review, each showed that green coffee extract was significantly more effective than a placebo in lowering body weight.
While the researchers admitted the studies were poorly designed, they concluded that there was enough congruence to suggest that green coffee was a safe and potentially beneficial weight loss aid.
A 2013 review of studies published in the Journal of Evidence-Based Integrative Medicine went even further.In their review five clinical trials and one meta-analysis, the researchers reported that people lost between 1 kilogram (kg) to 8 kg of body weight—or roughly 2 to 17 pounds—as a result of green coffee extract.
As with the 2011 review, the conclusions were limited by the generally poor quality of the reviewed studies.
Chlorogenic acid is one of the most abundant polyphenols in the foods we eat. Polyphenols are plant-based chemicals with antioxidant properties. They not only fight free radicals that damage cells, but they are also believed to help regulate blood sugar (glucose).
A 2010 study reported that chlorogenic acid delivered at a dose of 5 milligrams per kilogram (mg/kg) of body weight was able to normalize glucose levels in diabetic rats.4
In humans, the daily consumption of three to four cups of decaffeinated coffee containing high concentrations of chlorogenic acid reduced the risk for type 2 diabetes by 30 percent, according to 2009 research from Australia.
While it is presumed that green coffee, which has higher quantities of chlorogenic acid, may provide even greater protection, this has yet to proven in research.
3.High Blood Pressure
There is evidence that green coffee can lower blood pressure. According to a 2006 study from Japan, green coffee extract prescribed at 140 mg per day for 12 weeks reduced the systolic blood pressure by 5 mmHg and diastolic blood pressure by 3 mmHg in mildly hypertensive adults.
While encouraging, this doesn't mean that green coffee will benefit everyone with high blood pressure. This is especially true for people with caffeine sensitivity in whom green coffee may trigger the same symptoms as regular coffee, including increased blood pressure.Interestingly, none of the participants in the Japanese trial experience changes in weight or body mass.
As far-fetched as it may seem, green coffee can potentially prevent or reduce some of the cognitive and neuropsychiatric symptoms of Alzheimer's disease.Chlorogenic acid has a weak stimulatory effect, about a third as potent as caffeine. While it doesn't give anywhere near the same "kick" as caffeine, it can elevate moods and with less risk of jitteriness or irritability.
The benefits of green coffee in colorectal cancer prevention is even less clear.On the one hand, animal studies have long shown how polyphenols in coffee can help protect against the formation of colon tumors.7 It has been suggested that green coffee, which is composed of 14 percent chlorogenic acid, may enhance this effect.
On the flip side, coffee contains compounds that may increase the risk of colorectal cancer, either by promoting the mutation of cells or causing breakdown of cellular DNA. Whether these carcinogenic compounds are created during the roasting of the beans is not yet clear.
Green coffee and green coffee extracts are generally considered safe for adults. With that being said, little is known about the long-term safety of green coffee extract or supplements.
As with regular coffee, green coffee may cause side effects, particularly those with caffeine sensitivity. These include:
Increased heart rate
Ringing in the ears (tinnitus)
There is some concern that the long-term or excessive consumption of green coffee may increase the risk homocysteinemia (the excessive buildup of the amino acid homocysteine linked to heart disease and miscarriage).
There are no known drug interactions with green coffee.
green coffee bean extract dosage
There is no standardized dosing recommendation for green coffee extracts or supplements. Generally speaking, it is best to stay within the recommended dose on the product label if only to avoid side effects..
Green coffee bean extract contains caffeine, a stimulant linked to weight loss. It also boasts high levels of chlorogenic acid, a polyphenol antioxidant that researchers speculate may promote weight loss by reducing the absorption of fat and glucose in the gut, and lowering insulin levels to improve metabolic function.
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