What is grape seed extract good for
May 20, 2021

Grape Seed Extract Benefits

1.Can reduce blood pressure

Several studies have researched the effects of GSE on high blood pressure.A review of 16 studies in 810 people with high blood pressure or an elevated risk of it found that taking 100–2,000 mg of GSE daily significantly reduced systolic and diastolic blood pressure (the top and bottom number) by an average of 6.08 mmHg and 2.8 mmHg, respectively.

2. Can improve blood flow

Some studies suggest that GSE may improve blood flow. In an 8-week study in 17 healthy postmenopausal women, taking 400 mg of GSE had blood-thinning effects, potentially reducing the risk of blood clots.

An additional study in 8 healthy young women assessed the effects of a single 400-mg dose of proanthocyanidin from GSE immediately followed by 6 hours of sitting. It was shown to reduce leg swelling and edema by 70%, compared with not taking GSE.

In the same study, 8 other healthy young women who took a daily 133-mg dose of proanthocyanidins from GSE for 14 days experienced 40% less leg swelling after 6 hours of sitting.

3. Could reduce oxidative damage

An elevated blood level of LDL (bad) cholesterol is a known risk factor for heart disease. The oxidation of LDL cholesterol significantly increases this risk and plays a central role in atherosclerosis, or the buildup of fatty plaque in your arteries.

GSE supplements have been found to reduce LDL oxidation triggered by high fat diets in several animal studies.

4. May improve collagen levels and bone strength

Increasing flavonoid consumption may improve collagen synthesis and bone formation. As a rich source of flavonoids, GSE may thus help increase your bone density and strength.

In fact, animal studies have found that adding GSE to either a low calcium, standard, or high calcium diet can increase bone density, mineral content, and bone strength.


Animal studies show promising results regarding GSE’s ability to help treat arthritic conditions and promote collagen health. However, human-based research is lacking.

grape seed extract benefits

5. Supports your brain as it ages

Flavonoids’ combination of antioxidant and anti-inflammatory properties are thought to delay or reduce the onset of neurodegenerative diseases like Alzheimer’s disease.

One of the components of GSE is gallic acid, which animal and lab studies have shown can inhibit the formation of fibrils by beta-amyloid peptides.Clusters of beta-amyloid proteins in the brain are characteristic of Alzheimer’s disease.

6. Can improve kidney function

Your kidneys are particularly susceptible to oxidative damage, which is often irreversible.Animal studies have shown that GSE may reduce kidney damage and improve function by reducing oxidative stress and inflammatory damage.

7. Can inhibit infectious growth

GSE displays promising antibacterial and antifungal properties.Studies have shown that GSE inhibits the growth of common foodborne bacteria, including Campylobacter and E. coli, both of which are often responsible for severe food poisoning and abdominal upset.

8. May reduce cancer risk

The causes of cancer are complex, though DNA damage is a central characteristic.A high intake of antioxidants, such as flavonoids and proanthocyanidins, are associated with a reduced risk of various cancers.

9. May protect your liver

Your liver plays an important role in detoxifying harmful substances introduced to your body through drugs, viral infections, pollutants, alcohol, and more.

GSE appears to have a protective effect on your liver.

10. Enhances wound healing and appearance

Several animal studies have found GSE can aid wound healing.

Human studies show promise as well.

In one such study, 35 healthy adults who had undergone minor surgery were given either a 2% GSE cream or placebo. Those using the GSE cream experienced full wound healing after 8 days, while the placebo group took 14 days to heal.

What is grape seed extract for

What is grape seed extract for

Grape seed extract (Vitis vinifera) is a natural substance available in capsule and tablet form. It is usually sourced from grape seeds provided by wine manufacturers. Grapes and grape seed extract have a long history of culinary and medicinal use.

Is grape seed extract good for high blood pressure

The two extract doses were "equally efficient in lowering the blood pressure," researcher C. Tissa Kappagoda, MD, PhD, tells WebMD. Kappagoda specializes in cardiovascular medicine at the University of California at Davis.

Systolic blood pressure (the top number in a blood pressure reading) dropped 12 points, on average. Diastolic blood pressure (the bottom number in a blood pressure reading) dropped an average of 8 points, Kappagoda says.

is grape seed extract good for pregnancy

Given the lack of evidence about its safety, grape seed extract is not recommended for children or for women who are pregnant or breastfeeding.

is grape seed extract good for thyroid

This study scrutinised the ameliorative properties of grape seed extract (GSE) in dexamethasone (DEX)-induced testicular and thyroid dysfunction associated with oxidative stress in male albino rats. Thirty-two healthy adult male albino rats were divided into four groups of eight animals each: normal, DEX control, DEX + GSE (200 mg/kg body weight) group and DEX + GSE (400 mg/kg body weight) group. The body weight gain and testes weight were assessed.

Plasma testosterone and thyroid profile were determined. Testicular glucose-6-phosphate dehydrogenase (G-6-PDH), acid phosphatase (ACP), total protein and glutathione (GSH) levels, as well as catalase (CAT) activity also histopathological changes of the testis were evaluated. DEX treatment caused a significant decrease in body weight gain and weight of testes. Significant alterations in enzymatic and nonenzymatic antioxidants were observed. Moreover, a marked reduction in plasma testosterone levels and thyroid profile was observed. The administration of GSE significantly attenuated the deleterious effects of oxidative stress induced by DEX, as well as attenuated DEX-induced testicular and thyroid damage. Furthermore, DEX induced histological alterations in the testis. GSE ameliorated the injurious effects of DEX and improved the histological alterations in the testis.

Is grape seed extract good for varicose veins

Grape seed extract is a powerful antioxidant that may help to alleviate health problems associated with free radical damage. It also exerts a beneficial influence on blood vessels and is useful for conditions such as varicose veins. It may also be beneficial in the treatment of certain cardiovascular conditions and eye disease related to diabetes.

is grape seed extract good for hair

In hair products, Grape Seed Extract is commonly used as a deep moisturizer, sealant, shine enhancer, and heat protector from blow drying and flat ironing.

It has a worldwide cult-like fan club thanks to its ability to increase shine, softness, and silkiness. Some call it an Rx for their damaged hair, as it prevents frizz, mends split ends, and helps keep hair stronger and healthier so it can grow longer. Those with curly texture love it because it helps define and moisturize their coils while being lightweight enough to not weigh down their locks.

Grape Seed also contains a high content of vitamin E, which is fantastic for natural sun protection, and keeps hair color from fading.


Grape Seed Extract refers to a set of derivatives made from whole grape seeds. Ours at Prose are grown in vineyards in France. Once seeds are dried, they are extracted at 40 degrees Celsius in a two-hour process using only green solvents. The low temperature helps maintain the integrity of the active nutrient molecules, while extracting the maximum amount of target compounds.


In one study, a sample of Caucasian hair was washed with a shampoo and then treated with Grape Seed Extract. The hair was rinsed with water and dried using a hair dryer. A physical stress test that combined wetting hair using a water spray and drying using a hair dryer was repeated 10 times. The hair was then washed, filtered, and the concentration of proteins in the filtrate was determined. Results showed that hair damage was reduced by 77% after five drying cycles and 60% after 10. This indicates that Grape Seed Extract protects hair against damage caused by hair dryers on a long-term basis.

is grape seed extract good for diabetics

Grape seed extract may help to lower blood sugar and glucose levels in patients with diabetes mellitus, according to a Chinese study.

Researchers at the College of Food Science of Shenyang Agricultural University gave oral grape seed extract supplements to diabetic rats. Those that were given procyanidin fractions were compared to a controlled group that received none.

At six weeks, they found that the grape seed extract (procyanidin oligomers) was found to have a stronger anti-diabetic effect in rats with diabetes.

Previous studies have demonstrated that the resveratrol that is found in grape seed extract may help to ward off cancer, in addition to healing skin wounds, inhibiting oral sugar metabolism, slowing the growth of bacteria in dental infection, and improving liver function.

Patients with diabetes mellitus on a modified diet who are not currently taking anti-diabetic medications cannot manage their glucose levels normally, which can lead to hyperglycemia or high blood sugar.

is grape seed extract good for prostate

is grape seed extract good for prostate

A recently completed study at two UCHealth locations suggests that a commonly used, relatively inexpensive product, grape seed extract, could benefit some men with prostate cancer.

hand in a tub of grapes. Could grape seed extract help slow the spread of prostate cancer?

A small recently completed study at UCHealth suggests that extract from the seeds of grapes could help slow the spread of cancer in men with non-metastatic prostate cancer.

Grape seed extract is readily available in pill, capsule and liquid form on the aisles of health food and grocery stores. Many people take it as a dietary supplement – it contains antioxidants and may help to reduce inflammation and lower blood pressure, although studies of those benefits are sparse.

By contrast, grape seed extract has been the subject of National Institutes of Health-funded studies for well over a decade at the Skaggs School of Pharmacy and Pharmaceutical Sciences on the University of Colorado Anschutz Medical Campus. There, Drs. Chapla Agarwal and Rajesh Agarwal and their research colleagues isolated a specific compound in grape seed extract that not only inhibits the growth of prostate cancer tumors but also causes the cells that drive the growth to die.

That success, published in 2014, followed many years of lab work by the Agarwals that established the cancer-fighting properties of grape seed extract in cell cultures and in mice. For example, in 2009, they published a study summarizing evidence from their own studies and others that grape seed extract administered to mice was effective in slowing the growth of not only prostate but also skin, colorectal and breast cancers.

From bench to bedside: Grape seed extract for prostate cancer

This and other work provided the foundation for the current study, led by Dr. Paul Maroni, associate professor of Surgery-Urology at the University of Colorado School of Medicine. Maroni met with Rajesh Agarwal about the feasibility of a clinical trial that would test the effectiveness of grape seed extract in treating human patients with prostate cancer. They put together a trial protocol, based not on hope, but on the years of evidence the Agarwals had developed.

is grape seed extract good for dogs

Grape seed extract is a strong antioxidant that helps to support the immune system. It can also have an anti-inflammatory effect and so is often recommended for dogs with allergic skin conditions. Unlike whole grapes, grape seed extract is not toxic to dogs.

Best time to take grape seed extract

Grape seed extract is generally considered safe with few side effects. Dosages of around 300–800 mg per day for 8–16 weeks have been found to be safe and well tolerated in humans.

For bulk grape seed extract powder, contact us at email:


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