The study found that green tea extract inhibited the expression of high fat-induced obesity and pro-inflammatory genes. In the B group of experiments, mice fed the high-fat mixed green tea extract lost 20% of their body weight and their insulin resistance levels were lower than those of the high-fat diet group without the green tea extract.
Green tea extract also promotes the growth of the intestinal flora of mice, thereby reducing the risk of obesity. Researchers have shown that mice that consume green tea extract have a relatively healthier microflora. In group A mice, green tea extract did not reduce the body weight of the mice, but reduced endotoxin and beneficially altered some intestinal bacterial populations. Compared with group A, the diversity of intestinal microbes in high-fat mice fed green tea extract in group B increased, and the ratio of thick-walled bacteria: Bacteroidetes decreased (intestinal thick-walled bacteria more than Bacteroidetes) It is easier to absorb the heat in the food and lead to obesity).
The study provides evidence that green tea can reduce the body weight of obese mice and promote the growth of intestinal bacteria to reduce the risk of obesity. So how much green tea extract does the mouse eat? Want to get a similar effect, how much tea does humans drink every day? The researchers pointed out that this amount is about 10 cups of green tea a day.
Green tea polyphenols improve skeletal muscle metabolism
Obesity, spleen and thirst are a continuous pathological process and a transitional stage of the diabetes trilogy. Dietary supplements, nutraceuticals, and botanicals have become another way to alleviate complications in patients with type 2 diabetes (T2DM).
Existing studies have shown that compounds such as green tea polyphenols (GTP) and tocotrienols (TT) will also be selected as potent candidates for the treatment of hyperglycemia, hyperinsulinemia and skeletal muscle diseases, which reduce inflammation and maintain oxidation - The antioxidant balance provides a promising treatment.
Skeletal muscle is the main site of glucose uptake and plays an important role in insulin resistance in type 2 diabetes. The researchers selected obese mice with insulin resistance and hyperglycemia to study the relationship between glucose homeostasis and skeletal muscle metabolism. In this study, 48 male rats were fed high-fat foods and randomly assigned to 4 groups (the diet contained no tocotrienol, 400 mg/kg tocotrienol and no green tea polyphenols in water, 0.5 % vol/wt green tea polyphenol) was tested for 14 weeks.
The results show that green tea polyphenols and tocotrienols can have beneficial effects on the body, improve glucose homeostasis, reduce lipid peroxidation, increase the rate-limiting enzyme of oxidative phosphorylation, and improve the bones of obese mice. Muscle metabolism. The synergistic effect of green tea polyphenols and tocotrienols also increases muscle fiber cross-sectional area (CSA) and is therefore useful for preventing muscle atrophy in patients with insulin resistance and hyperglycemia.
Green tea is the second largest consumption of beverages after water and is grown in at least 30 countries. Nowadays, green tea-related products are not limited to the beverage industry. Skin care, cakes, food and other fields have provided opportunities for green tea to show more talents. Statistics show that in 2018, the national tea production was 2.616 million tons, while the output of green tea reached 1,722,400 tons, accounting for 65.8% of China's total tea production. In recent years, China's green tea production has shown a steady growth trend, and demand has further expanded, and its future development prospects are very broad.