How much coq10 should i take
May 25, 2021

How much coq10 should i take

There is no established ideal dose of CoQ10. Studies have used doses of CoQ10 ranging from 50 milligrams to 1,200 milligrams in adults, sometimes split into several doses over the course of a day. A typical daily dose is 100 milligrams to 200 milligrams. Follow the instructions on the bottle or get advice from your doctor or a dietitian. Keep in mind that different supplement brands might have different ingredients and strengths.

How much coq10 should i take for fertility

Research has found that dietary antioxidants — including CoQ10 — may help reduce oxidative stress and improve fertility in both men and women.

Supplementing with 200–300 mg per day of CoQ10 has been shown to improve sperm concentration, density and motility in men with infertility.

Similarly, these supplements may improve female fertility by stimulating ovarian response and help slow ovarian aging.

CoQ10 doses of 100–600 mg have been shown to help boost fertility.

How much coq10 should i take

How much coq10 should i take with crestor

For people taking statin medications, the typical dosage recommendation for CoQ10 is 30–200 mg per day

How much coq10 should i take per day

Conventional wisdom states that the body needs high levels of CoQ10 supplementation because so little of the supplement is able to penetrate the mitochondrial membrane. Fortunately, MitoQ’s highly absorbable formula means that people can use less than ten times the normal CoQ10 concentrations and still receive greater benefits to their mitochondrial health. While traditional supplements might recommend taking 500 to 1200 mg of CoQ10 per day, MitoQ is effective in a dose of just 10 mg taken once per day. Taking 10 mg per day of highly absorbable MitoQ can help maintain general health and wellbeing, support mental focus, support healthy aging, sustain energy levels and help overall cellular and human health for added resilience and vitality. 

How much coq10 should i take with red yeast rice

Statins may deplete the coenzyme called CoQ10 from the body. CoQ10 is very important in heart and muscle health and in energy production. Side effects of CoQ10 depletion include fatigue, muscle aches and pains, and muscle damage. Red yeast rice also may deplete CoQ10 from the body. It is important to supplement your diet with CoQ10, 150 - 200 mg at night, while you are taking red yeast rice products, and for 4 weeks after you stop taking red yeast rice.

How much coq10 should i take for hypertension

How much coq10 should i take for hypertension

If you are on treatment for hypertension, the addition of CoQ10 supplements may allow you to decrease the dosage of other antihypertensive drugs. With that said, there is no guarantee that they will, and you should never change doses unless your doctor gives you the OK. Regular monitoring of blood pressure is needed before any such judgments can be made.

COQ10 should only be taken by adults 19 and older. Recommended dosages range from 30 mg to 200 mg daily, depending on the manufacturer. Soft gel capsules are thought to be absorbed better than other formulations.

How much coq10 should i take for migraines

For treating migraines, the typical dosage recommendation for CoQ10 is 300–400 mg per day.

How much coq10 should i take to get pregnant

For the purpose of improving fertility, women usually take 300 – 600mg of CoQ10 per day. You should stop the supplement if you become pregnant, because the safety of high dose CoQ10 has not been studied in pregnancy. People taking Warfarin should not take CoQ10. Side effects of CoQ10 are generally mild and limited to stomach upset.

How much coq10 should i take to lower blood pressure

Regular monitoring of blood pressure is needed before any such judgments can be made.

COQ10 should only be taken by adults 19 and older. Recommended dosages range from 30 mg to 200 mg daily, depending on the manufacturer. Soft gel capsules are thought to be absorbed better than other formulations.

How much coq10 should i take with lipitor

However, other studies have shown no effect, emphasizing the need for more research on this topic.

For people taking statin medications, the typical dosage recommendation for CoQ10 is 30–200 mg per day.

Coenzyme Q10 (CoQ10) is a coenzyme found in all animals and most bacteria. Present in all respiring eukaryotic cells, CoQ10 is primarily found in the mitochondria, where it plays a role in the generation of adenosine triphosphate (ATP). Because of the body’s reliance on ATP for most of its energy, CoQ10 is found in higher concentrations in organs that require the most energy—the heart, liver and kidneys.1

Naturally occurring in the body and found in many foods, including meat, fish, soybean and, to a lesser extent, fruits, nuts and vegetables, CoQ10 is also sold as a dietary supplement and in functional foods targeted toward those who, due to age or underlying condition, do not produce satisfactory levels themselves.

coq10 benefits

Coq10 benefits

CoQ10 is perhaps best known for two functions: its role in the conversion of glucose and fatty acids to ATP and its role as a powerful antioxidant in cells.

CoQ10 can exist in three oxidation states: the fully reduced form ubiquinol (CoQ10H2), the radical semiquinone intermediate (CoQ10H·) and the fully oxidized ubiquinone (CoQ10).2 While most CoQ10 products on the market are in the oxidized ubiquinone state, “it is ubiquinol that provides virtually all of benefits associated with CoQ10,” writes Gene Bruno, professor of nutraceutical science and Provost of Huntington College of Health Sciences.2 When the human body is supplemented with ubiquinone, it must first convert it to its fully reduced ubiquinol form. If it is not converted, the ubiquinone will remain inactive, leading Bruno to claim, “in fact, ubiquinol may be thought of as the ‘active antioxidant’ form of CoQ10.”

CoQ10 supplementation is used to help address symptoms of a range of ailments, including diabetes, chronic migraines, statin-induced myopathy and cardiovascular conditions.1 However, because of its lipophilic nature, the issue of absorption and bioavailability is one that must be cleared for effective supplementation.


Patients with diabetes exhibit significantly lower levels of plasma CoQ10 compared to healthy individuals.3 This deficiency of CoQ10 “may further impair the body’s defensive mechanisms against oxidative stress induced by hyperglycemia in diabetes.” A 2018 pooled analysis on the effects of CoQ10 on overweight and obese patients with type 2 diabetes showed “several studies have demonstrated that the restoration of CoQ10 levels in patients with diabetes by the supplemental use of exogenous CoQ10 could potentially preserve mitochondrial function, alleviate oxidative stress and eventually lead to improvement of glycemic control.”

Additionally, the pooled analysis found CoQ10 to be well-tolerated, with no drug-related adverse reactions, and concluded “our findings provide substantial evidence that daily CoQ10 supplementation has beneficial effects on glucose control and lipid management in overweight and obese patients with [Type 2 diabetes].”3


CoQ10 has also been hypothesized to be useful in migraine prevention.4 This suggests migraines result in deficiencies in mitochondrial energy in the brain, since CoQ10 plays “an important role in sustaining mitochondrial energy stores,” according to the researchers. Additionally, CoQ10 “counteracts endothelial dysfunction [which may be linked to migraine attacks] by stimulating endothelial release of nitric oxide and has anti-inflammatory effects.”5

A 2007 study by Hershey et al. on 1,550 children and adolescents suffering chronic migraines showed that roughly one-third of them had CoQ10 levels below reference range.6 The study went on to note that supplementation of this subgroup with 1 to 3 mg/kg/d of CoQ10 “improved coenzyme Q10 level, headache frequency and disability.”

In a 2005 double-blind, randomized, placebo-controlled clinical trial, adult patients with migraines were treated with 100 mg/d of CoQ10 orally for three months.7 The trial concluded that supplementation “significantly decreased the frequency of migraine attacks.”

3.Statin-induced Myopathy

Statins are a class of lipid-reducing drugs often used to treat high cholesterol and reduce the risk of cardiovascular disease (CVD). However, it is estimated that around 10 to 15% of people who take statins experience resultant muscle problems, often in the form of pain and/or weakness and referred to as statin-induced myopathy.

A 2018 meta-analysis by Qu et al. on the effects of CoQ10 on statin-induced myopathy found, “[CoQ10] supplementation ameliorated statin‐associated muscle symptoms, such as muscle pain, muscle weakness, muscle cramps and muscle tiredness.”8 The meta-analysis went on to explain why this finding is so important, stating, “Coenzyme Q10 supplementation provided a complementary approach to statin‐associated muscle symptoms, which would be significant for the patients with cardiovascular diseases who are intolerant to statin treatment because of statin‐associated muscle symptoms.”

4.Cardiovascular health

CoQ10 has been shown to treat various cardiovascular disorders, including angina.4 One meta-analysis of eight controlled clinical trials concluded that “treatment of [congestive heart failure with CoQ10] revealed a significant improvement in several important cardiac parameters, such as ejection fraction, stroke volume, cardiac output, cardiac index and end diastolic volume index.”


Pure CoQ10 is lipophilic, meaning it is insoluble in water, creating challenges for brands attempting to market effective doses.“This lipophilic nature makes CoQ10’s absorption poor, highly variable and strongly dependent on stomach contents,” said Steve Holtby, president and CEO, Soft Gel Technologies Inc. (SGTI). “CoQ10 is a large molecule, also contributing to its poor absorption.”

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