Grape Skin Extract and Grape Seed Extract: Exploring the Benefits and Differences
Grapes are not only delicious and refreshing, but they also offer various health benefits, thanks to their high content of antioxidants and bioactive compounds. Two of these compounds - grape skin extract and grape seed extract - have gained popularity in recent years due to their potential health benefits. In this article, we will explore what grape skin extract and grape seed extract are, their benefits, and how they differ from each other.
The focus of this review is on the research into the health benefits of grape seed and skin extract (GSSE). Important polyphenolic substances with high biological activity are abundant in GSSE. GSSE's effects on diabetes mellitus, cardiovascular disease, and cancer, its neuroprotective effect, its effects on the gastrointestinal tract, and other health complications associated with these diseases are summarized in this review. The studies show that "Vitis vinifera L." seed extract has anti-inflammatory, anti-apoptotic, and pro-proliferative effects that lower oxidative stress and improve lipid metabolism in general.
What is Grape Skin Extract?
Grape skin extract is a supplement made from the outer layer of grapes, which contains high amounts of flavonoids, anthocyanins, and resveratrol. These compounds are known for their potent antioxidant and anti-inflammatory effects, as well as their ability to support cardiovascular health, cognitive function, and immune system function.
Flavonoids are a group of plant compounds that have been shown to have various health benefits, including reducing inflammation, lowering blood pressure and cholesterol levels, and protecting against cellular damage. Anthocyanins are pigments responsible for the red, blue, and purple colors of grapes, and they have been associated with improved cognitive function and reduced risk of chronic diseases such as cancer, diabetes, and cardiovascular disease. Resveratrol is a polyphenol that is found in grape skins, as well as in red wine, and has been shown to have anti-aging and anti-inflammatory effects, as well as potential for preventing or treating several diseases.
The varieties of Vitis vinifera that are grown in Marlborough, New Zealand, are the source of Grape Skin Extract. Using a proprietary process called "100% Aqua Pure," it is naturally extracted from grapes that have not been fermented. Water is all that is used in this process, and no harsh chemicals or ethanol are used.
The majority of commercial grape skin extract is made from grapes that have already been fermented to make red wine. Bleaching is used in this procedure to get rid of the anthocyanins in the grape skins. Additionally, ethanol and other solvents are used in the extraction process to remove components from the grape skins.
Grape Skin Extract aims to provide the powdered form of the health benefits of red wine. Compared to other grape skin extracts, it contains a lot of phenols and other active ingredients.
Grape skin extract benefits
There is growing evidence to support the potential health benefits of grape skin extract, some of which include:
1. Protecting against oxidative stress: Grape skin extract's high antioxidant content can help protect cells from oxidative damage caused by free radicals, which can lead to chronic diseases such as cancer, heart disease, and Alzheimer's disease.
2. Supporting cardiovascular health: Grape skin extract has been shown to lower blood pressure, reduce inflammation and oxidative stress, and improve blood flow, all of which are important for maintaining cardiovascular health and lowering the risk of heart disease and stroke.
3. Improving cognitive function: Several studies have suggested that grape skin extract, particularly its high anthocyanin content, can improve cognitive performance and memory in both young and elderly adults.
4. Boosting immune system function: Grape skin extract's immunomodulatory effects may help support the body's immune defenses, leading to a reduced risk of infections and better overall health.
What is Grape Seed Extract?
The wine grapes' seeds are used to make the chemical substance known as grape seed extract. Most of the time, it is promoted as a supplement for a variety of conditions. This includes reducing inflammation, promoting wound healing, and venous insufficiency. Proanthocyanidins are typically the components of grape seed extract.
In addition to red wine, red cabbage, green and black tea, and various berries like strawberries, cranberries, blueberries, and bilberries, proanthocyanidins are potent free radical scavengers. When grape seed extract is applied topically to the skin of human volunteers, it may increase the sun protection factor, according to some studies. In addition, when compared to vitamins C and E, grape seed extract is a significantly more potent free radical scavenger.
Grape Seed Extract benefits
Some of the potential health benefits of grape seed extract include:
1. Reducing inflammation: Grape seed extract's high antioxidant content can help reduce inflammation throughout the body, which is a major cause of chronic diseases such as cardiovascular disease, cancer, and arthritis.
2. Supporting cardiovascular health: Grape seed extract has been shown to improve arterial function, lower blood pressure, and reduce oxidative stress, all of which are important for maintaining cardiovascular health.
3. Improving skin health: Grape seed extract's proanthocyanidin content can help protect against UV damage, reduce inflammation, and improve collagen synthesis, leading to healthier, more youthful-looking skin.
4. Supporting cognitive function: Several studies have suggested that grape seed extract may improve cognitive function, particularly in older adults.
5.Supports brain functions
Numerous human studies have demonstrated that a moderate amount of red wine, which contains a high concentration of resveratrol, can prevent cognitive decline. Also, it stops the brain from making protein fragments (beta-amyloid), which cause Alzheimer's disease in older people. On the other hand, one animal study has shown that the gallic acid in GSE prevents the brain from making fibrils, which can cause a number of brain diseases. Additionally, GSE effectively enhances cognitive abilities by preventing memory loss and forming brain amyloid clusters.
difference between resveratrol and grape seed extract/Grape Seed Extract vs resveratrol
Resveratrol and grape seed extract differ primarily in that resveratrol comes from grape skins, whereas grape seed extract comes from grape seeds. Medical research shows that grape seed extract and resveratrol work very well together to kill cancer cells in the colon.
It has been discovered that resveratrol and grape seed extract both possess significant antioxidant properties. For neutralizing free radicals, antioxidant activities are crucial. Oxygen molecules that are unstable make up free radicals, which trigger oxidative reactions and have the potential to cause DNA damage or even cell death.
The oligomeric proanthocyanidin complexes (OPCs) that grape seed extract contains appear to be the primary source of its antioxidant benefits. Anthocyanins, flavonoids, phenolic acids, and, most importantly, resveratrol are just a few of the other ingredients in it.
Resveratrol, on the other hand, is a potent antioxidant that can be found in grapes and many other plants. Both resveratrol and grape seed extract can greatly assist in protecting cells, tissues, and organs from damage or aging by neutralizing free radicals, thereby preventing a variety of health conditions, including heart disease, cancer, and stroke.
In addition, resveratrol is frequently referred to as a phytoestrogen or plant-based estrogen due to its potential to function similarly to the estrogen hormone.
Both grape seed extract and resveratrol are potent antioxidants found in grapes, but they differ in several ways:
1. Source: Resveratrol is found primarily in grape skins, while grape seed extract is made from the seeds.
2. Bioavailability: Resveratrol is poorly absorbed by the body, meaning that high doses are needed to achieve therapeutic effects, while grape seed extract has higher bioavailability and can be absorbed more easily.
3. Mechanisms of action: Although both compounds have potent antioxidant and anti-inflammatory effects, they may work through different pathways.
4. Potential health benefits: Resveratrol has been studied extensively for its potential health benefits, including reducing inflammation, improving heart health, and preventing cancer, while grape seed extract has been shown to support cardiovascular health, cognitive function, and skin health.
Grape skin extract resveratrol
Since grape skin extract contains resveratrol, it can offer some of the same potential health benefits, including reducing inflammation, protecting against oxidative damage, and improving cardiovascular health. However, grape skin extract may offer additional benefits due to its high anthocyanin content.
Grape seed extract vs pycnogenol
Pycnogenol is a trademarked supplement made from the bark of the French maritime pine tree, which is rich in proanthocyanidins. Like grape seed extract, pycnogenol has been shown to have strong antioxidant and anti-inflammatory effects, as well as potential benefits for cardiovascular health, skin health, and cognitive function.
However, grape seed extract may offer some advantages over pycnogenol, including:
1. Availability: Grape seed extract is more widely available and cheaper than pycnogenol.
2. Bioavailability: Grape seed extract has higher bioavailability than pycnogenol, meaning that it can be absorbed more easily by the body.
3. Mechanisms of action: Although both supplements act primarily through antioxidant and anti-inflammatory mechanisms, grape seed extract may offer different benefits due to its unique composition.
Related to: https://www.underherb.com/info/pine-bark-extract-vs-grape-seed-extract-54850161.html
Grape seed extract for skin lightening
Due to its high proanthocyanidin content, grape seed extract has been studied for its potential skin-lightening effects. One study showed that a cream containing grape seed proanthocyanidins was effective in reducing hyperpigmentation in women with melasma, a common skin condition characterized by dark patches on the face.
However, further research is needed to confirm grape seed extract's skin-lightening effects, as well as its safety and effectiveness for long-term use.
Who should not take grape seed extract?
Although grape seed extract is generally safe for most people when taken in recommended doses, there are some groups who should avoid it or consult with a healthcare provider before use, including:
1. Pregnant or breastfeeding women: There is limited research on the safety of grape seed extract for pregnant and breastfeeding women, so it is best to avoid it or consult with a healthcare provider before use.
2. Individuals taking blood thinners: Since grape seed extract may have blood-thinning effects, it should be avoided by those taking blood thinners or with bleeding disorders.
3. Individuals with allergies: Some people may be allergic to grapes or grape products, including grape seed extract, so it is important to check for allergies before use.
Which is better grape seed extract or resveratrol?
Both grape seed extract and resveratrol have unique health benefits and can be beneficial for different health conditions. However, since grape seed extract has higher bioavailability, it may be more effective at lower doses and for certain conditions, such as skin health and cardiovascular function.
Ultimately, the best supplement for you will depend on your specific health needs and goals, as well as your medical history and any underlying health conditions. It is best to consult with a healthcare provider before taking any new supplements or making major changes to your diet or lifestyle.
References:https://www.differencebetween.com/what-is-the-difference-between-resveratrol-and-grape-seed-extract/
https://www.xtend-life.com/blogs/supplement-ingredients/grape-skin-extract
https://purovitalis.us/blogs/nutrition/grape-seed-extract-vs-resveratrol-the-benefits-comparison
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696942/
https://vorstcanada.com/blogs/news/grape-seed-extract-vs-resveratrol