What is Natural Berberine?
Natural Berberine and Sanguinarine alkaloids belong to a group of naturally occurring chemical compounds that mostly contain basic nitrogen atoms. This group also includes some related compounds with neutral or weakly acidic properties. Alkaloids are produced by a large number of organisms including bacteria, fungi, plants, and animals.
Natural Berberine and Sanguinarine both are isoquinoline derivatives and belong to protoberberine and benzophenanthridines, respectively. Tyrosine or phenylalanine is common precursor for the biosynthesis of both. Sanguinarine [13-methyl (1,3) benzodioxolo(5,6-c)-1,3-dioxolo (4,5) phenanthridinium] is a toxin that kills animal cells through its action on the Na+-K+-ATPase transmembrane protein. Berberine, on the other hand, has been reported to cause cytotoxicity and adversely influence the synthesis of DNA.

Natural Berberine Manufacturer Specification:
| Name | Natural Berberine |
| CAS Number | 2086-83-1 |
| Molecular Formula | C20H18NO4+ |
| Molecular Weight | 336.37 g/mol |
| Appearance | Yellow crystalline powder |
| Purity | 97% |
| Test Method | Titration |
| Solubility | Slightly soluble in water, soluble in alcohol |
| Melting Point | 204–206°C |
| Boiling Point | 486.8 ℃ |
| Storage Conditions | Store in a cool, dry place, away from light |
| Shelf Life | 2 years |
| Heavy Metals (Pb) | < 10 ppm |
| Arsenic (As) | < 2 ppm |
| Lead (Pb) | < 3 ppm |
| Microbial Limits | Total Plate Count < 1,000 CFU/g |
| Bacterial Contamination | Absence of E. Coli, Salmonella |
| Packaging | 25Kg/Drum or Custom Required |

Advantages of Natural Berberine
- Natural source: Natural berberine is extracted from plants and has not been artificially synthesized. Natural ingredients are generally more compatible with the physiological mechanisms of the human body and may be more easily absorbed and utilized by the body.
- Complex effect: Natural berberine is usually not just a single ingredient. Berberine extracted from plants is usually accompanied by other phytochemicals (such as flavonoids, polyphenols, saponins, etc.), which may work synergistically to exert a comprehensive effect. This complex effect may be a unique advantage of natural berberine.
- Less artificial intervention: Natural berberine is usually less artificially chemically intervened and is relatively pure and original.
- Strong consumer trust: Natural berberine is usually highly trusted by consumers because of its natural source, especially those who prefer natural remedies and plant-based products.
The Best Natural Berberine Supplier
Undersun enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our products, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you'll have great tasting our products on-time.
We also focus on value-added services. We are available for service questions and information to support your business.

20 Years of Natural Ingredients Factory
We provide organic solutions and innovation for almost 20 industries across more than 150 countries, including food & beverages, superfoods, dietary supplements, vegan foods.
Choose Undersun to help you get better benefits.
Why Choose Undersun Natural Berberine?
Undersun specialize in pure berberine for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.
Where to buy Natural Berberine?
Just send email to herbext@undersun.com.cn, or submit your requirement in bottom form, we are of service at any time!
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