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Product Name:shiitake powder
Appearance:Brown powder
Plant Part:Plant of mushroom
Specification:Polysaccharides 10%30%60%
Particle size:100% pass 80 mesh
Loss on drying:5.0%
Package:Plastic bags; Aluminum foiled bags or as customer request
Shelf life:2 years
Certifications: ISO,KOSHER,Halal,Organic;
Test Method: UV;
Stock in LA USA warehouse;

What is Lentinan?

Lentinan is a polysaccharide isolated from the fruit body of shiitake mushroom (Lentinula edodes mycelium).Lentinan is a β-1,3 beta-glucan with β-1,6 branching. It has a molecular weight of 500,000 Da and specific rotation of +14-22° (NaOH).

An in vitro experiment showed lentinan stimulated production of white blood cells in the human cell line U937.Lentinan is thought to be inactive in humans when given orally and is therefore administered intravenously. The authors of an in vivo study of lentinan suggested that the compound may be active when administered orally in mice.

lentinan extract

Basic Information:

Product name

Shiitake Powder

Latin name

Lentinus edodes

Part used

Whole herb

Extraction Type

Solvent Extraction

Active Ingrdients



flower mushroom,

Test Method



Polysaccharide 30-50% Brown yellow powder


Medicine, food additives

buy lentinan

Lentinan Benefits:

Lentinan is a substance that comes from the shiitake mushroom. Medical professionals use lentinan to boost the effects of regular medicines used for treating cancer and HIV infection. They give lentinan intravenously (by IV) or as a shot (by injection).

1. Antitumor activity of lentinan

Lentinus edodes polysaccharide has an anti-tumor effect, and it has no toxic side effects of chemotherapy drugs. After the lentinan enters the antibody, it induces an immunologically active cytokine. Under the combined action of these cytokines, the body’s immune system is enhanced and it plays a defense and killing effect on the tumor cells.

Lentinus edodes polysaccharide enhances antibody-dependent cell-induced cytotoxicity (ADDC) by activating macrophages, and exerts anti-tumor activity; in addition, lentinan can cause blood vessel dilatation and hemorrhage at the tumor site, resulting in tumor hemorrhage, necrosis and complete degeneration.

2. Immunomodulation of lentinan

The immunomodulatory effects of lentinan extract are an important basis for its biological activity. Lentinus edodes is a typical T cell activator that promotes the production of interleukins and promotes the function of mononuclear macrophages. It is considered to be a special immune enhancer. Its immune function is characterized by its ability to promote the production of lymphocyte activating factor (LAE), release various helper T cell factors, enhance the phagocytic rate of host peritoneal macrophages, and restore or stimulate the function of helper T cells. In addition, lentinan also promotes antibody production and inhibits macrophage release.

3. Antiviral activity of lentinan

Dr. Ishida of Japan believes that shiitake mushrooms contain a double-stranded ribonucleic acid that stimulates the release of interferon from human reticular cells and white blood cells, while interferon has an antiviral effect. The mycelium extract of shiitake mushroom can inhibit the adsorption of herpes virus by cells, thereby preventing various diseases caused by herpes simplex virus and cytomegalovirus. The United Kingdom extracts a substance from the cultured shiitake mycelium, which can restore the HIV-infected T lymphocytes, stimulate macrophages, help produce antibodies to treat AIDS, and is safe and has no side effects.

Some scholars have found that sulfated lentinan has anti-HIV (HIV) activity, which can interfere with the adsorption and invasion of retroviruses and other viruses. Japanese scholars have reported that a sulfated derivative of glucan with good anti-tumor activity obtained from the fruiting body of Lentinus edodes can inhibit the activity of HIV.

4. Anti-infective effect of lentinan

It has been reported that lentinan extract can increase macrophage function. Lentinus edodes polysaccharide has inhibitory effects on Abelson virus, adenovirus type 12 and influenza virus infection, and is a good drug for treating various hepatitis, especially chronic migratory hepatitis.

Shiitake Mushroom Extract-1

Undersun's Lentinan

Competitive advantage:

Selected raw materials, Sufficient stock, quick shipment from USA warehouse, own manufacturer produce and export directly, price advantage and good service, Timely communication, strong technical service team, mixing and blending as customer’s formula

Quality Standard:

Conform to QB standards.

Production process flow chart:

Shitake Mushroom raw material →Screening→Extracted with water→Filtration→


Packing & Storage :

Packing: 25Kg/Fiber Drum, double plastic bag inside.

1Kg/Bag, aluminum foil bag vacuum packing

Or customized.
Storage: Kept away from strong light and heat.
Shelf Life: 24 months for powder


Logistics transportation:


Payment term:


FAQ ( Do You Want To Place An Order With Us Now? )

Riley Gao,


Can i get some samples?


Yes, we can supply the free sample, but the shipping cost be paid by our customers.


How to start orders or make payments?


Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Escrow.


What's your MOQ?


Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.


How about leading time?


Leading time: About 3-5 days after payment confirmed.


Is there a discount?


Different quantity has different discount.


How do you treat quality complaint?


First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

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