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Gymnema Sylvestre Extract

Gymnema Sylvestre Extract

Product:Gymnema Extract
Specification:25% 75%
Part Used: Leaf
Test Method:By W/W
Appearance: Brown fine powder
Advantage :Bulk stock in USA warehouse,Hot sale in USA Marketing;
Application :Use for health care product and food additive;

What is Gymnema Sylvestre Extract?

Gymnema sylvestre extract is a perennial, woody climber that has a long history of medicinal use in Ayurvedic medicine. It belongs to the class dicotyledonous of the family Asclepiadaceae or “milkweed” family.

You can find gymnema slyvestre growing in tropical and subtropical regions, especially parts of central and southern India, tropical African, and some parts of China, Malaysia and Sri Lanka.

Gurmar gymnema sylvestre extract have been used in the ancient Indian medicinal practice Ayurveda for thousands of years.It has been a traditional remedy for various ailments, including diabetes, malaria and snakebites

gurmar gymnema sylvestre extract

Basic Information:

Product Name:Gymnema Extract
Part used:Bark
Appearance:Brown yellow powder
Active ingredientGymnemic acid
Test methodTLC
Shelf life:24 months
Storage:Cool dry place


Physical&Chemical Data

AppearanceFine PowderOrganoleptic
Analytical Quality

IdentificationIdentical to R.S. sampleHPTLC
Gymnemic Acids≥75.0%W/W
Sieve analysis100 % through 80 meshUSP36<786>
Loss on Drying≤5.0 %Eur.Ph.7.0 [2.8.17]
Total Ash≤10.0 %Eur.Ph.7.0 [2.4.16]
Bulk density40~60 g/100mLEur.Ph.7.0 [2.9.34]
Tap density60~90g/100mLEur.Ph.7.0 [2.9.34]

Lead (Pb)≤3.0 mg/kgEur.Ph.7.0<2.2.58>ICP-MS
Arsenic (As)≤2.0 mg/kgEur.Ph.7.0<2.2.58>ICP-MS
Cadmium (Cd)≤1.0 mg/kgEur.Ph.7.0<2.2.58>ICP-MS
Mercury (Hg)≤0.1 mg/kgEur.Ph.7.0<2.2.58>ICP-MS
Solvents ResidueMeet Eur.Ph.7.0 <5.4>Eur.Ph 7.0<2.4.24>
Pesticides ResidueMeet USP RequirementsUSP36 <561>

Total Plate Count≤10000 cfu/gUSP36 <61>
Yeast &Mold≤1000 cfu/gUSP36 <61>
E.Coli.NegativeUSP36 <62>
SalmonellaNegativeUSP36 <62>

Gymnema Sylvestre leaf extract benefits

Gymnema Sylvestre Extract Benefits

1. Gymnema Sylvestre in diabetes type 2

Gymnema sylvestre extract contains gymnemic acids, which not only suppress the taste of sugar in the body temporarily but also used to treat diabetes and related disorders.

2. Gymnema in weight loss

Gymnema decreases cravings for sweets and reduces food intake. Consuming less food can lead to a decrease in calorie intake and thus helps in weight loss. Gymnema sylvestre standardized extract also help diminish the absorption of glucose and fat from the gut.

3. Managing cholesterol levels - Higher levels of cholesterol in blood enhance the risk of heart and various other circulatory diseases. Gurmar gymnema sylvestre extract, with its antioxidant properties, tends to avoid the absorption of this harmful cholesterol and triglycerides in the intestine. The saponin contents of gymnemic acids may dissolve the greasy cholesterol and promotes its excretion from the body.

4. High Blood Pressure:

High blood pressure may result due to various factors like obesity, diabetes, and high cholesterol levels, even oxidative stress can cause an increase in the systolic blood pressure. All these factors tend to activate the angiotensin II enzyme, which is responsible for increasing the blood pressure. The extracts of Gymnema Sylvestre can suppress the levels of leptin, lipids, insulin, reduce the levels of oxidative stress damage, and blocks the activities of the angiotensin system II. This action aids in the reduction of high blood pressure.

5. Managing PCOS symptoms

PCOS is a metabolic syndrome that results due to obesity, defects in the hypothalamic-pituitary axis, impaired insulin secretion, and dysregulated ovarian function. It has been validated through several studies that insulin resistance not only causes diabetes but also promotes PCOS by increasing the production of androgen in theca cells. Studies have also enumerated the beneficial role of Gymnema Sylvestre in treating PCOS by enhancing insulin sensitivity, promoting insulin secretion and thus decreasing the production of androgen.

6. Anti-cancer activity

Studies have shown that ethanolic extract of Gymnema sylvestre extract exhibited antiproliferative effects by effectively scavenging the nitrite radicals that damage the cells or lead to abnormal growth of cells. Gymnema, apart from exerting antiproliferative effects, also showed potent anti-inflammatory activity and acted as natural antioxidants do. It has been found beneficial in preventing the oxidative stress-related degenerative diseases.

7. Immunomodulatory effect

Gymnema Sylvestre modulates the immune system through various immunostimulatory activities which include

8. Anti-ulcer effect

Various components of gurmar gymnema sylvestre extract, like saponins, resins, tannins, alkaloids, flavonoids, glycosides, and sterols, were found to produce anti-ulcer effects. The extracts of Gymnema may improve the impaired gastric emptying and intestinal transit while also reducing the free acid content, gastric volume, and total acidity. It also neutralizes the acid content of the stomach by increasing the pH of gastric juice.

gymnema sylvestre application

Gymnema Sylvestre Extract Application:

1.Pharmaceutical health care products

2.Health supplements

3.Infant food, solid beverage, dairy products, instant food, snack food, spice, middle-aged and old food, baking food, snack food, cold food cold drinks, etc.

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