Turmeric is a commonly used drug, and its main biologically active ingredients are curcumin and volatile oil. The former has the effects of lowering blood fat, anticoagulation, anti-oxidation, choleretic, anti-cancer, etc.; while the latter mainly plays an anti-inflammatory, anti-bacterial and anti-cough effect. Curcumin exerts its anticancer effect by inducing differentiation of malignant tumor cells, inducing apoptosis of tumor cells and inhibiting tumor growth in various stages, and is widely used clinically.
Curcumin is a plant polyphenol extracted from turmeric, and it is also the most important active ingredient of turmeric. Recent studies have not only proved the traditional role of turmeric, but also revealed some new pharmacological effects, such as anti-inflammatory, anti-oxidation, scavenging oxygen free radicals, anti-human immunodeficiency virus, protecting liver and kidney, anti-fibrosis and anti-cancer. Anti-cancer effects may be related to the inhibition of the activation and expression of transcription factors such as nuclear factor-κB and activator-1, and have no obvious side effects.
Animal experiments at Duke University in the United States have shown that curcumin in curry not only decomposes amyloid in the brain of mice, but also prevents the production of this protein. Researchers have pointed out that eating curry may also have a similar effect on people, which helps prevent Alzheimer's disease.
Many studies have shown that large accumulation of amyloid in the brain is one of the most important causes of senile dementia. Previous studies have shown that curcumin, a key ingredient in curry, has the effect of preventing damage to brain nerve cells and improving brain nerve cell function.
According to US media reports, researchers at Duke University in the United States genetically engineered mice to produce many amyloid proteins in their brains. The researchers then provided curcumin-rich foods to the rats, and found that the amyloid in the brain of the rats was broken down, and the same recipe prevented the mice from developing amyloid in the adult brain.
Inflammation is a complex process that is triggered by cellular infections and/or tissue damage, and a series of chain reactions that ultimately lead to the rapid development of certain chronic diseases. Since inflammation plays an important role in most chronic diseases, anti-inflammatory drugs are needed to prevent it. Although a number of different steroidal and non-steroidal anti-inflammatory drugs such as semecoxib, aspirin, ibuprofen, phenylbutazone, etc. can be used to treat inflammatory diseases, most of them have side effects. Studies have found that the anti-inflammatory activity of curcumin is comparable to steroidal and non-steroidal drugs such as indomethacin and phenylbutazone, and is safe in most cases.
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